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What are Opioids?

Opioids are a group of drugs that are used for treating pain. They are derived from opium which comes from the poppy plant.

Opioid (Narcotic) Pain Medications

When you have a mild headache or muscle ache, an over-the-counter pain reliever is usually enough to make you feel better. But if your pain is more severe, your doctor might recommend something stronger — a prescription opioid.

Opioids are a type of narcotic pain medication. They can have serious side effects if you don’t use them correctly. For people who have an opioid addiction, their problem often started with a prescription.

If you need to take opioids to control your pain, here are some ways to make sure you’re taking them as safely as possible.

How Opioids Work

Opioid drugs bind to opioid receptors in the brain, spinal cord, and other areas of the body. They tell your brain you’re not in pain.

They are used to treat moderate to severe pain that may not respond well to other pain medications.

Opioid drugs include:

  • Codeine (only available in generic form)
  • Fentanyl (Actiq, Duragesic, Fentora, Abstral, Onsolis)
  • Hydrocodone (Hysingla, Zohydro ER) 
  • Hydrocodone/acetaminophen (Lorcet, Lortab, Norco, Vicodin)
  • Hydromorphone (Dilaudid, Exalgo)
  • Meperidine (Demerol)
  • Methadone (Dolophine, Methadose)
  • Morphine (Kadian, MS Contin, Morphabond)
  • Oxycodone (OxyContin, Oxaydo)
  • Oxycodone and acetaminophen (Percocet, Roxicet)
  • Oxycodone and naloxone

Your doctor can prescribe most of these drugs to take by mouth. Fentanyl is available in a patch. A patch allows the medication to be absorbed through the skin.

Working With Your Doctor

You’ll need a prescription from your doctor before you start taking opioids. The doctor can adjust the dose as needed to help control pain.

You may receive around-the-clock doses to manage pain throughout the day and night. And your doctor may prescribe opioids to be taken “as needed” in case you have “breakthrough” pain — a flare of pain that you get despite round-the-clock doses.

While you’re on opioid pain medications, check in with your doctor regularly. Your doctor will need to know:

  • How your pain is responding to the drug
  • Whether you’re having any side effects
  • Whether you have any potential interactions or medical conditions that could make you more likely to have side effects, such as sleep apnea, alcohol use, or kidney problems
  • Whether you’re taking the drug properly

Opioid vs Opiate vs Narcotic

The term opiates refers to natural or slightly modified components of opium such as codeine, morphine and heroin. The term opioids was originally used for synthetic opiates such as Oxycontin and Fentanyl. But now is used for the entire class of drugs. Narcotics is an older name originally referring to any mind-altering compound with sleep-inducing properties.

Opioid Withdrawal

Opioid withdrawal can be extremely uncomfortable. The important thing to remember is that opioid withdrawal is not life threatening if you are withdrawing only from opioids and not a combination of drugs. (Drug and alcohol withdrawal is different for each drug. Alcohol withdrawal and benzodiazepine withdrawal are potentially dangerous)

Common Drug Names and Brand Names of Opioids/Anxiety

Adderall 10mg (Amphetamine and Dextroamphetamine)

Adderall 10mg (Amphetamine and Dextroamphetamine)


Ambien (Zolpidem) 10 mg

Ambien (Zolpidem) 10 mg


Demerol 50 Mg (Meperidine Hydrochloride)

Demerol 50 Mg (Meperidine Hydrochloride)


Dilaudid (Hydromorphone) 8 mg

Dilaudid (Hydromorphone) 8 mg


ENDOCET 10MG/325MG (OXYCODONE AND ACETAMINOPHEN)

Endocet 10 mg/325 mg (Oxycodone And Acetaminophen)


Hydrocodone Bitartrate 5mg 325mg

Hydrocodone Bitartrate 5mg/325mg


Hydrocodone Bitartrate 5mg/325mg

Hydrocodone Bitartrate 5mg/325mg


Hydrocodone Bitartrate 7.5mg/325mg

Hydrocodone Bitartrate 7.5mg/325mg


Hysingla 30mg (Hydrocodone Bitatrate)

Hysingla 30mg (Hydrocodone Bitatrate)


Klonopin (clonazepam) 2 mg

Klonopin (Clonazepam) 2 mg


Morphine Sulfate 80 mg

Morphine Sulfate 80 mg


Morphine Sulfate 100 mg

Morphine Sulfate 100 mg


Oxycodone 30 mg

Oxycodone 30 mg


Oxycodone 80 mg

Oxycodone 80 mg


Oxymorphone Hydrochloride 30 mg

Oxymorphone Hydrochloride 30 mg


Percocet 10mg/650mg (Acetaminophen/Oxycodone)

Percocet 10mg/650mg (Acetaminophen/Oxycodone)


Roxicodone 30 mg

Roxicodone 30 mg


Subutex 2 Mg

Subutex 2 Mg


Tramadol 200 mg

Tramadol 200 mg


Valium Diazepam 10 mg

Valium Diazepam 10 mg


Vicodin 10mg/300mg

Vicodin 10mg/300mg


Xanax (Alprazolam) 2 mg

Xanax (Alprazolam) 2 mg